Pliant Therapeutics Logo (identification only, no affiliation)

Pliant Therapeutics

Pliant Therapeutics Inc is a clinical-stage biopharmaceutical company developing novel therapies for fibrosis and related diseases, with a focus on integrin and TGF-β pathway inhibition.

Pliant Therapeutics Logo

About Pliant Therapeutics

Pliant Therapeutics Inc is a clinical-stage biopharmaceutical company focused on discovering, developing, and commercializing novel therapies for the treatment of fibrosis and related diseases. Its lead candidate, bexotegrast, is an oral, small-molecule dual selective inhibitor of avß6 and avß1 integrins, in phase 2b trials for idiopathic pulmonary fibrosis and phase 2a for primary sclerosing cholangitis. The company is also developing PLN-1474 for liver fibrosis, PLN-101095 for solid tumors, and PLN-101325 for muscular dystrophies. Pliant's approach targets fibrotic tissue-specific inhibition of integrins and the TGF-β pathway.

Address

260 Littlefield Avenue,
South San Francisco, 94080
United States

Year founded

2015

Number of employees

100-200

Sector

Health Care

Industry Group

Pharmaceuticals, Biotechnology & Life Sciences

Industry

Biotechnology

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